Yes. Google has published Android Enterprise for Android XR documentation, confirming management support for XR headsets and wired glasses.
Management is possible on fully managed devices only. There is no work profile - COPE or BYOD - support. EMMs may use AMAPI or a custom DPC.
The XR validation requirements are adapted from the standard mobile set:
For a detailed analysis including the full feature comparison with mobile validation, see Android Enterprise lands on Android XR.