Yes, in certain circumstances.
Google Play Protect runs on all GMS-certified Android devices, including those under enterprise management. If Play Protect identifies an app as potentially harmful, it can:
This applies regardless of how the app was installed - including apps pushed by the EMM or sideloaded as part of an enterprise workflow. On managed devices, this can be particularly disruptive for:
What can administrators do?
Best practice: test all deployed applications against Play Protect in a staging environment before fleet-wide deployment. Monitor for Play Protect warnings in device reports and respond promptly to avoid workflow disruption.
Play Protect's cloud scanning of sideloaded apps on managed devices was removed in September 2024, but on-device detection continues. See the related FAQ: Has Play Protect changed how it handles sideloaded apps on managed devices?.